Hamman-Rich syndrome medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

There is no effective treatment for acute interstitial pneumonitis, includes supportive therapy and glucocorticosteroids.

Supportive care

• Patients with acute interstitial pneumonitis receive supportive care alongside the medical therapy:
  • Supplemental oxygen
  • Mechanical ventilation
  • Prevention of complications
    • Venous thromboembolism
    • Gastrointestinal bleeding
    • Hospital-acquired pneumonia
    • Sepsis
• Pulmonary rehabilitation
• Vaccination against possible causes of pulmonary inflammation as influenza and pneumococcal vaccines.

Medical Therapy

• Corticosteroid therapy:
  • Once the diagnosis of acute interstitial pneumonitis is confirmed, high doses of glucocorticosteroids (eg, methylprednisolone) should be administered.
  • Monitor the patient for glucocorticosteroid-induced side effects (eg, hyperglycemia, increased susceptibility to infection, gastritis).
• Immunosuppressive therapy