Osteoarthritis (OA) is a result of variety of of disorders leads to structural and functional failure in a involved joints.
occurs when the cartilage that cushions the ends of bones in your joints gradually deteriorates. Cartilage is a firm, slippery tissue that permits nearly frictionless joint motion.
In osteoarthritis, the slick surface of the cartilage becomes rough. Eventually, if the cartilage wears down completely, you may be left with bone rubbing on bone.
Osteoarthritis is the clinical and pathological outcome of a range of disorders that results in structural and functional failure of synovial joints.2 Traditionally, it has been considered a disease of articular cartilage. The current concept holds that osteoarthritis involves the entire joint organ, including the subchondral bone, menisci, ligaments, periarticular muscle, capsule, and synovium