Temporal arteritis laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hamid Qazi, MD, BSc [2]
Overview
An elevated/reduced concentration of blood erythrocyte sedimentation rate (ESR) is suggestive of temporal arteritis. Laboratory findings consistent with the diagnosis of temporal arteritis include normochromic anemia, deceased albumin level, elevated alkaline phosphatase, and elevated C-reactive protein. Some patients with temporal arteritis may have elevated concentration of interleukin-6, which is usually suggestive of progression.
Laboratory Findings
- An elevated/reduced concentration of blood erythrocyte sedimentation rate (ESR) is suggestive of temporal arteritis.[37,84]
- Laboratory findings consistent with the diagnosis of temporal arteritis include:
- Anemia-normochromic[82]
- Albumin level is decreased
- Liver enzymes-elevated alkaline phosphatase
- C-reactive protein-elevated
- Interleukin-6-elevated serum interleukin (IL)-6 concentrations appear to be related closely to clinical disease activity in GCA [88] and may better correlate with clinical relapse than the ESR [89]