Ankylosing spondylitis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Common complications of ankylosing spondylitis include heterotopic ossification, skeletal restrictions and extra-musculoskeletal complications like eye problems, reduced flexibility,tiredness,osteoporosis and gastrointestinal disorders.Prognosis is generally good if diagnosed in early stages.
Natural History, Complications, and Prognosis
Natural History[1][2]
- The natural history of ankylosing spondylitis(AS) remains poorly documented.
- The heterogeneity of the ankylosing spondylitis(AS) has made studies technically difficult.
- Documentation of the early course of ankylosing spondylitis(AS) has been limited by the lack of appropriate criteria to diagnose early.
- Modified New York criteria had played important role in the study of ankylosing spondylitis(AS).
- Rudwaleit pointed that ankylosing spondylitis(AS) passes through three stages [3][4]
- Pre-radiographic
- Radiographic sacroiliitis
- Radiographic spinal changes
References
- ↑ Goie The HS, Steven MM, van der Linden SM, Cats A (August 1985). "Evaluation of diagnostic criteria for ankylosing spondylitis: a comparison of the Rome, New York and modified New York criteria in patients with a positive clinical history screening test for ankylosing spondylitis". Br. J. Rheumatol. 24 (3): 242–9. PMID 3160423.
- ↑ Robertson LP, Davis MJ (December 2004). "A longitudinal study of disease activity and functional status in a hospital cohort of patients with ankylosing spondylitis". Rheumatology (Oxford). 43 (12): 1565–8. doi:10.1093/rheumatology/keh386. PMID 15353608.
- ↑ Rudwaleit M, Landewé R, van der Heijde D, Listing J, Brandt J, Braun J, Burgos-Vargas R, Collantes-Estevez E, Davis J, Dijkmans B, Dougados M, Emery P, van der Horst-Bruinsma IE, Inman R, Khan MA, Leirisalo-Repo M, van der Linden S, Maksymowych WP, Mielants H, Olivieri I, Sturrock R, de Vlam K, Sieper J (June 2009). "The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part I): classification of paper patients by expert opinion including uncertainty appraisal". Ann. Rheum. Dis. 68 (6): 770–6. doi:10.1136/ard.2009.108217. PMID 19297345.
- ↑ van den Berg R, van der Heijde DM (November 2010). "How should we diagnose spondyloarthritis according to the ASAS classification criteria: a guide for practicing physicians". Pol. Arch. Med. Wewn. 120 (11): 452–7. PMID 21102381.