Buerger's disease laboratory findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
There are no diagnostic laboratory findings associated with Buerger's disease. Lab testing is done to exclude other vasculitides, such as lupus, scleroderma and mixed connective tissue disease.
Laboratory Findings
- There are no diagnostic laboratory findings associated with Buerger's disease.[1][2]
- Laboratory testing is performed to exclude other pathologies, and include:
- Acute phase reactants that indicate an active inflammatory process:
- Immunologic panel to rule out autoimmune disease:
- Antinuclear antibody
- Rheumatoid factor
- Anticentromere antibody
- Antiphospholipid antibodY
- Serum creatinine
- Complement
- SCL-70
- To rule out hypercoagulability:
- Complete blood count
- Liver function test
- PT, PTT and INR
- Antiphospholipid antibodies
- Anticardiolipin antibodies
- Protein C and S
- Antithrombin III
- Factor V Leiden
- Prothrombin gene mutation
- Toxicology screen
- Cocaine
- Amphetamine
- Cannabis
References
- ↑ Piazza G, Creager MA (April 2010). "Thromboangiitis obliterans". Circulation. 121 (16): 1858–61. doi:10.1161/CIRCULATIONAHA.110.942383. PMC 2880529. PMID 20421527.
- ↑ Olin JW (September 2000). "Thromboangiitis obliterans (Buerger's disease)". N. Engl. J. Med. 343 (12): 864–9. doi:10.1056/NEJM200009213431207. PMID 10995867.