Mixed connective tissue disease CT
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Differentiating Mixed connective tissue disease from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2]
Overview
CT scan
- Computed tomography may be helpful in early diagnosis of interstitial lung disease.[1]
- In MCTD, the tomographic images may show radiographic abnormalities related to interstitial lung disease and the presence of esophageal dilatation:[2][3]
- Areas of increased attenuation in which the bronchi and vessels remain visible (ground glass opacities)
- Irregularity of the interfaces between the peripheral pleura and aerated lung parenchyma or small lines perpendicular to the pleura (Interface sign)
- Septal and nonseptal lines (linear opacities)
- Intralobular reticular opacities
- Bronchiolectasis or traction bronchiectasis: dilatation of the airways in the peripheral portion of the lungs
- Areas of cystic spaces (diameter <1 cm) with thickened walls (honeycombing)
- Areas of decreased attenuation and air trapping on expiratory computed tomography
- Esophageal dilatation (esophagus may be fluid filled or has an air-fluid level)
References
- ↑ Végh J, Szilasi M, Soós G, Dévényi K, Dezso B, Soltész P, Zeher M, Szegedi G, Bodolay E (November 2005). "[Interstitial lung disease in mixed connective tissue disease]". Orv Hetil (in Hungarian). 146 (48): 2435–43. PMID 16408383.
- ↑ Fagundes MN, Caleiro MT, Navarro-Rodriguez T, Baldi BG, Kavakama J, Salge JM, Kairalla R, Carvalho CR (June 2009). "Esophageal involvement and interstitial lung disease in mixed connective tissue disease". Respir Med. 103 (6): 854–60. doi:10.1016/j.rmed.2008.12.018. PMID 19201182.
- ↑ Kozuka T, Johkoh T, Honda O, Mihara N, Koyama M, Tomiyama N, Hamada S, Nakamura H, Ichikado K (April 2001). "Pulmonary involvement in mixed connective tissue disease: high-resolution CT findings in 41 patients". J Thorac Imaging. 16 (2): 94–8. PMID 11292211.