Folate deficiency risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Risk Factors
Strong risk factors include :
- Low dietary folate intake
- Age >65 years
- Alcoholism
- Pregnant or lactating mothers
- Prematurity
- Intestinal malabsorptive disorders e.g. celiac disease, tropical sprue, jejunal resection, inflammatory bowel diseases.
- Use of drugs e.g. trimethoprim, methotrexate, anticonvulsants, sulfasalazine, or pyrimethamine
- Infantile intake of goats' milk which is low in folate content
- Congenital defects in folate absorption and metabolism
Weaker risk factors inlcude :
- States of increased cell turnover e.g. chronic hemolysis
- Intake of special diet
- Chronic dialysis