Folate deficiency classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Some situations that increase the need for folate may lead to folate deficiency in the body. These include: Hemorrhage, kidney dialysis, liver disease, malabsorption e.g. celiac disease, pregnancy and lactation, and alcohol consumption. Some medications and Some congenital disorders can also lead to folate deficiency.
Medication
Medications can interfere with folate utilization, including:
- Anticonvulsant medications e.g phenytoin
- Metformin
- Methotrexate, an anti-cancer drug also used as an anti-inflammatory
- Sulfasalazine, used in Inflammatory bowel syndrome
- Birth control pills
Congenital
- Defects in folate metabolism
- Defects in folate absorption
Classification
Folate deficiency can be classified as follows :
Situational
Some situations that increase the need for folate may lead to folate deficiency in the body. These include:
- Hemorrhage
- Kidney dialysis
- Liver disease
- Malabsorption e.g. celiac disease
- Pregnancy and lactation
- Alcohol consumption
Medication
Medications can interfere with folate utilization, including:
- Anticonvulsant medications e.g phenytoin
- Metformin
- Methotrexate, an anti-cancer drug also used as an anti-inflammatory
- Sulfasalazine, used in Inflammatory bowel syndrome
- Birth control pills
Congenital
- Defects in folate metabolism
- Defects in folate absorption