Paroxysmal nocturnal hemoglobinuria historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Historical Perspective
The first description of paroxysmal hemoglobinuria was by the German physician Paul Strübing (1852).[1][2]A more detailed description was made by Dr Ettore Marchiafava and Dr Alessio Nazari in 1911,[3] with further elaborations by Marchiafava in 1928[4] and Dr Ferdinando Micheli in 1931.[5]
Discovery
- [Disease name] was first discovered by [name of scientist], a [nationality + occupation], in [year]/during/following [event].
- The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
- In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
- In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
Outbreaks
There have been several outbreaks of [disease name], which are summarized below:
Landmark Events in the Development of Treatment Strategies
In [year], [diagnostic test/therapy] was developed by [scientist] to treat/diagnose [disease name].
Impact on Cultural History
Famous Cases
The following are a few famous cases of disease name:
References
- ↑ Strübing P. Paroxysmale Hämoglobinurie. Dtsch Med Wochenschr 1882;8:1-3 and 17-21.
- ↑ Whonamedit entry
- ↑ Marchiafava E, Nazari A. Nuovo contributo allo studio degli itteri cronici emolitici. Policlinico [Med] 1911;18:241-254.
- ↑ Marchiafava E. Anemia emolitica con emosiderinuria perpetua. Policlinico [Med] 1928;35:105-117.
- ↑ Micheli F. Uno caso di anemia emolitica con emosiderinuria perpetua. G Accad Med Torino 1931;13:148.