Lupus nephritis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]
Overview
Lupus Nephritis was first discovered by Osler and Jadassohn, two physicians, in 1948 by the discovery of the LE cell in 1948. The word "lupus" means wolf in Latin, as the destructive injuries SLE causes brought to mind wolf bites. The history of lupus erythematosus can be divided into three periods: classical, neoclassical, and modern. The classical period mostly refers to ancient history, when there was no exact definition of the disease. During the neoclassical lupus era, scientists investigated the manifestations of lupus and worked to define the disease's action. Modern history is mostly focused on a microscopical understanding of the disease and pathogenesis of SLE.
Historical Perspective
Discovery
The word "lupus" means wolf in Latin, as the destructive injuries SLE causes brought to mind wolf bites. The history of lupus erythematosus can be divided into three periods: classical, neoclassical, and modern[1]. The classical period mostly refers to ancient history, when there was no exact definition of the disease. During the neoclassical lupus era, scientists investigated the manifestations of lupus and worked to define the disease's action. Modern history is mostly focused on a microscopical understanding of the diseaseand pathogenesis of SLE.
Classical History
- In ancient times, it was believed that lupus patients could turn into wolves, especially when exposed to sunlight. This false belief was later found to be related to lupus photosensitivity.[2]
- Hippocrates was the first to use the phrase "herpes esthiomenos," which was a definition for lupus lesions. Thus, Hippocrates is considered the first to have described cutaneous ulceration of the disease.
Outbreaks
- For more information, see Systemic lupus erythematosus historical perspective
Landmark Events in the Development of Treatment Strategies
- For more information, see Systemic lupus erythematosus historical perspective
Impact on Cultural History
For more information, see Systemic lupus erythematosus historical perspective
Famous Cases
For more information, see Systemic lupus erythematosus historical perspective