Rapidly progressive glomerulonephritis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

RPGN was discovered in 1958 by Australians Stanton and Tait.

Historical perspective

• Ernst Goodpasture made case reports about glomerulnophritis and pulmonary haemorrhages in 1919.
• Stanton and Tait from Australia studied these case reports and then named the findings as Goodpasture syndrome. in 1958.
• They gave the anti GBM antibodies classification and discovered RPGN in these cases.
• In 1960s, electron microscopy and immunofluorescence helped learn RPNG on immunological level.