Disseminated intravascular coagulation physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Omer Kamal, M.D.[2]
Overview
Patients with [disease name] usually appear [general appearance]. Physical examination of patients with [disease name] is usually remarkable for [finding 1], [finding 2], and [finding 3].
OR
Common physical examination findings of [disease name] include [finding 1], [finding 2], and [finding 3].
OR
The presence of [finding(s)] on physical examination is diagnostic of [disease name].
OR
The presence of [finding(s)] on physical examination is highly suggestive of [disease name].
Physical Examination
Physical examination of patients with DIC is usually remarkable for the following:[1][2][3][4][5]
Hemtological:
- Signs of spontaneous and life-threatening hemorrhage
- Signs of subacute bleeding
- Signs of diffuse or localized thrombosis
- Bleeding into serous cavities
Nervous:
- Nonspecific altered consciousness or stupor
- Transient focal neurologic deficits
Cardiovascular:
- Hypotension
- Tachycardia
- Circulatory collapse
Respiratory:
- Pleural friction rub
- Signs of acute respiratory distress syndrome (ARDS)
Gastrointestinal:
- Hematemesis
- Hematochezia
Genitourinary:
- Signs of azotemia and renal failure
- Acidosis
- Hematuria
- Oliguria
- Metrorrhagia
- Uterine hemorrhage
Skin:
- Petechiae
- Jaundice (liver dysfunction or hemolysis)
- Purpura
- Hemorrhagic bullae
- Acral cyanosis
- Skin necrosis of lower limbs (purpura fulminans)
- Localized infarction and gangrene
- Wound bleeding and deep subcutaneous hematomas
- Thrombosis
References
- ↑ Miyashima Y, Iwamuro M, Shibata M, Miyabe Y, Kawai Y, Kaihara M, Mitogawa T, Harada M (January 2018). "Prediction of Disseminated Intravascular Coagulation by Liver Function Tests in Patients with Japanese Spotted Fever". Intern. Med. 57 (2): 197–202. doi:10.2169/internalmedicine.8420-16. PMC 5820036. PMID 29021432.
- ↑ Iba T, Arakawa M, Ohchi Y, Arai T, Sato K, Wada H, Levy JH (September 2018). "Prediction of Early Death in Patients With Sepsis-Associated Coagulation Disorder Treated With Antithrombin Supplementation". Clin. Appl. Thromb. Hemost.: 1076029618797474. doi:10.1177/1076029618797474. PMID 30198317.
- ↑ Kilicci C, Ozkaya E, Karakus R, Sanverdi I, Abide Yayla C, Bostanci Ergen E, Mutlu S (September 2018). "Early low molecular weight heparin for postpartum hemorrhage in women with pre-eclampsia. Is it effective to prevent consumptive coagulopathy?". J. Matern. Fetal. Neonatal. Med.: 1–5. doi:10.1080/14767058.2018.1494708. PMID 30189766.
- ↑ McBride AM (2018). "Clinical Presentation and Treatment of Amniotic Fluid Embolism". AACN Adv Crit Care. 29 (3): 336–342. doi:10.4037/aacnacc2018419. PMID 30185500.
- ↑ Judkins AJ, MacQueen BC, Christensen RD, Henry E, Snow GL, Bennett ST (September 2018). "Automated Quantification of Fragmented Red Blood Cells: Neonatal Reference Intervals and Clinical Disorders of Neonatal Intensive Care Unit Patients with High Values". Neonatology. 115 (1): 5–12. doi:10.1159/000491626. PMID 30184540.