Multiple sclerosis historical perspective

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Irfan Dotani

Overview

Multiple sclerosis was first described by a neurologist, Dr. Jean Martin Charcot in 1868 and named sclerose en plaque. The signs and symptoms including dysarthria, ataxia, and tremor were called 'Charcot’s triad'.

Historical Perspective

Discovery

• Multiple sclerosis was first described by a neurologist, Dr. Jean martin Charcot in 1868. Previously, Dr. Robert Hooper (1773-1835), Robert Carswell (1793-1857), and Jean Cruveilhier (1791-1873) had noticed some of the MS clinical manifestations, but for the first time, Dr. Charcot described it as a distinct disease and named sclerose en plaque.
• The signs and symptoms including dysarthria, ataxia, and tremor were called charcot’s triad.

Outbreaks

There are no outbreaks for Multiple sclerosis disese.

Impact on Cultural History

there is no evidence

Famous Cases

One of the first suspected MS patients in history is Saint Lidwina (1380-1433). She had symptoms such as pain, lower extremities weakness, and vision loss. The other MS suspected patient in history is Augustus Frederick d’este (1794-1848). His symptoms began at the age of 28 with vision loss, bladder dysfunction, numbness, weakness of legs and sexual dysfunction.