Mantle cell lymphoma other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]

Overview

Other diagnostic studies for the diagnosis of mantle cell lymphoma include bone marrow aspiration, lumbar puncture, colonoscopy, upper endoscopy, laparoscopy, and laparotomy.

Other Diagnostic Studies

Other diagnostic studies for the diagnosis of mantle cell lymphoma include:

• Bone marrow aspiration
• Lumbar puncture
• Colonoscopy
• Upper endoscopy
• Laparoscopy (rarely performed)
• Laparotomy (rarely performed)

Bone Marrow Aspiration

Mantle cell lymphoma is a systemic disease with frequent involvement of the bone marrow and the peripheral blood. There is also a not-uncommon leukemic phase, marked by presence in the blood. For this reason, both the peripheral blood and bone marrow are evaluated for the presence of malignant cells.

Lumbar Puncture

In some patients with the blastic variant, lumbar puncture is done to evaluate the spinal fluid for CNS involvement.

Colonoscopy

Since mantle cell lymphoma may present a lymphomatous polyposis coli and colon involvement is common, colonoscopy can be helpful in the diagnosis of MCL.

Upper Endoscopy

Upper endoscopy may be helpful in selected cases.