Hemophilia historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]
Overview
Hemophilia is considered a very old disease with its history dating back to the 2nd century AD. The first modern descriptions of the condition appeared during the 1800s. Extensive work has been done over the centuries regarding the classification, inheritance pattern, and treatment of hemophilia.
Historical Perspective
Discovery
- References to a condition associated with bleeding and suggestive of hemophilia date back to the 2nd century AD.[1][2]
- Ancient religious script compilations, such as The Babylonian Tarmud, have also mentioned the condition along with relative fatal bleeding episode prevention.[2][3]
- Abu Qasim Khalaf Ibn Abbas Al Zahrawi, a pioneer of modern surgery, known in the West as Albucasis or Zahravius, described potential hemophilia cases in the 10th century.
- G. W. Consbruch of Bielefeld, Germany, described a bleeding disease very similar to hemophilia in 1793.
- Dr John Conrad Otto, an American physician, is responsible for the first modern description of hemophilia in 1803. He described a bleeding disorder, transmitted via unaffected females and affecting only males.[4]
References
- ↑ Brinkhous, K. M. (1975). Handbook of hemophilia. Amsterdam New York: Excerpta Medica Sole distributors for the U.S.A. and Canada, American Elsevier Pub. Co. ISBN 9789021920962.
- ↑ 2.0 2.1 Rosendaal FR, Smit C, Briët E (February 1991). "Hemophilia treatment in historical perspective: a review of medical and social developments". Ann. Hematol. 62 (1): 5–15. PMID 1903310.
- ↑ Ingram, G. I. C. (1997). "The history of haemophilia*,†". Haemophilia. 3 (S1): 5–15. doi:10.1111/j.1365-2516.1997.tb00168.x. ISSN 1351-8216.
- ↑ Otto JC (July 1996). "An account of an hemorrhagic disposition existing in certain families". Clin. Orthop. Relat. Res. (328): 4–6. PMID 8653976.