Rhabdomyosarcoma epidemiology and demographics
|
Rhabdomyosarcoma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Rhabdomyosarcoma epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Rhabdomyosarcoma epidemiology and demographics |
|
Risk calculators and risk factors for Rhabdomyosarcoma epidemiology and demographics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Epidemiology and Demographics
- Rhabdomyosarcoma is considered as a most common soft tissue cancers among children and adolescents and it is the third most common extracranial solid tumors during childhood which comes after neuroblastomaand wilms tumor.[1][2]
- Rhabdomyosarcoma is responsible for 50% of soft tissue tumors during childhood and 5% of all pediatrics cancers.[3]
- Almost 350 new cases of rhabdomyosarcoma are diagnosed annually.[1]
Incidence
The overall incidence of rhabdomyosarcoma in children is 0.45 cases for 100,000 children and 50% of cases are seen in the first decade of life.[4] Incidence may depend on the histologic subtype of rhabdomyosarcoma:
- Embryonal rhabdomyosarcoma: Embryonal rhabdomyosarcoma peaks in 0 to 4 year age group at approximately 0.4 cases per 100,000 children, with a lower rate in adolescents, approximately 0.15 cases per 100,000 adolescents.
- Alveolar rhabdomyosarcoma: The incidence of alveolar rhabdomyosarcoma does not vary by gender and is constant from ages 0 to 19 years at approximately 0.1 case per 100,000 children and adolescents.
- Undifferentiated sarcoma: Infants younger than 1 year have a higher incidence of undifferentiated sarcoma.
Age
In general, rhabdomyosarcoma tends to affect individuals less than 45 years of age.
- Rhabdomyosarcoma is most commonly seen in children aged one to five years old. Overall, 65% of all rhabdomyosarcomas are diagnosed in patients under 10 years old.
- Less commonly, it can also present in teens aged 15 to 19, and can even develop in adulthood, though this is even more rare.
References
- ↑ 1.0 1.1 Dasgupta R, Fuchs J, Rodeberg D (2016). "Rhabdomyosarcoma". Semin Pediatr Surg. 25 (5): 276–283. doi:10.1053/j.sempedsurg.2016.09.011. PMID 27955730.
- ↑ Arndt CA, Crist WM (1999). "Common musculoskeletal tumors of childhood and adolescence". N Engl J Med. 341 (5): 342–52. doi:10.1056/NEJM199907293410507. PMID 10423470.
- ↑ Dasgupta R, Rodeberg DA (2012). "Update on rhabdomyosarcoma". Semin Pediatr Surg. 21 (1): 68–78. doi:10.1053/j.sempedsurg.2011.10.007. PMID 22248972.
- ↑ "Childhood Rhabdomyosarcoma Treatment".