Dimethylallyltranstransferase
| Dimethylallyltranstransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| File:2f8z.jpg | |||||||||
| Identifiers | |||||||||
| EC number | 2.5.1.1 | ||||||||
| CAS number | 9032-79-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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| Farnesyldiphosphate synthase (farnesylpyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | |
|---|---|
| Identifiers | |
| Symbol | FDPS |
| Entrez | 2224 |
| HUGO | 3631 |
| OMIM | 134629 |
| RefSeq | NM_002004 |
| UniProt | P14324 |
| Other data | |
| EC number | 2.5.1.1 |
| Locus | Chr. 1 q22 |
Dimethylallyltranstransferase (DMATT), also known as farnesylpyrophosphate synthase (FPPS) or as farnesyldiphosphate synthase (FDPS), is an enzyme that catalyzes the transformation of dimethylallylpyrophosphate (DMAPP) and isopentenyl pyrophosphate (IPP) into farnesylpyrophosphate (FPP).[1][2]
Pyrophosphate is also involved, as both a reactant and a product. Geranylpyrophosphate is created in an intermediate step.
See also
References
- ↑ Banthorpe DV, Bucknall GA, Doonan HJ, Doonan S, Rowan MG (1976). "Biosynthesis of geraniol and nerol in cell-free extracts of Tanacetum vulgare". Phytochemistry. 15: 91–100. doi:10.1016/s0031-9422(00)89061-5.
- ↑ Sagami H, Ogura K, Seto S, Kurokawa T (November 1978). "A new prenyltransferase from Micrococcus lysodeikticus". Biochemical and Biophysical Research Communications. 85 (2): 572–8. doi:10.1016/0006-291X(78)91201-9. PMID 736921.
External links
- Dimethylallyltranstransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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