ERRFI1

Revision as of 10:17, 23 June 2018 by imported>Bibcode Bot (Adding 0 arxiv eprint(s), 2 bibcode(s) and 0 doi(s). Did it miss something? Report bugs, errors, and suggestions at User talk:Bibcode Bot)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search
VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

ERBB receptor feedback inhibitor 1 is a protein that in humans is encoded by the ERRFI1 gene.[1][2][3][4][5]

MIG6 is a Cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000; Fiorentino et al., 2000).[supplied by OMIM][5]

Interactions

ERRFI1 has been shown to interact with Stratifin[6] and CDC42.[1]

References

  1. 1.0 1.1 Makkinje A, Quinn DA, Chen A, Cadilla CL, Force T, Bonventre JV, Kyriakis JM (Jul 2000). "Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stress". J Biol Chem. 275 (23): 17838–17847. doi:10.1074/jbc.M909735199. PMC 3668664. PMID 10749885.
  2. Chrapkiewicz NB, Davis CM, Chu DT, Caldwell CM, Granner DK (Oct 1989). "Rat gene 33: analysis of its structure, messenger RNA and basal promoter activity". Nucleic Acids Res. 17 (16): 6651–6667. doi:10.1093/nar/17.16.6651. PMC 318357. PMID 2780291.
  3. Fiorini M, Ballaro C, Sala G, Falcone G, Alema S, Segatto O (Sep 2002). "Expression of RALT, a feedback inhibitor of ErbB receptors, is subjected to an integrated transcriptional and post-translational control". Oncogene. 21 (42): 6530–6539. doi:10.1038/sj.onc.1205823. PMID 12226756.
  4. Fiorentino L, Pertica C, Fiorini M, Talora C, Crescenzi M, Castellani L, Alema S, Benedetti P, Segatto O (Oct 2000). "Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain". Mol Cell Biol. 20 (20): 7735–7750. doi:10.1128/MCB.20.20.7735-7750.2000. PMC 86354. PMID 11003669.
  5. 5.0 5.1 "Entrez Gene: ERRFI1 ERBB receptor feedback inhibitor 1".
  6. Benzinger, Anne; Muster Nemone; Koch Heike B; Yates John R; Hermeking Heiko (Jun 2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer". Mol. Cell. Proteomics. United States. 4 (6): 785–795. doi:10.1074/mcp.M500021-MCP200. ISSN 1535-9476. PMID 15778465.

Further reading