Rhabdomyosarcoma medical therapy
Rhabdomyosarcoma Microchapters |
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Rhabdomyosarcoma medical therapy On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
Treatment for rhabdomyosarcoma may consists of chemotherapy, radiation therapy and surgery. Chemotherapy may be given as neoadjuvant chemotherapy or adjuvant chemotherapy. Radiation therapy may be used as local therapy.
Medical Therapy
- Rhabdomyosarcoma treatment include combination of surgery, radiotherapy, and chemotherapy.
- Rhabdomyosarcoma treatments depends on staging classification and risk stratification. For more information click here.
Chemotherapy
Chemotherapy may be given as neoadjuvant chemotherapy or adjuvant chemotherapy. The most common drugs used to treat rhabdomyosarcoma are:[1]
Radiotherapy
- Radiation therapy may be used as local therapy. External beam radiation is used in some cases of rhabdomyosarcoma.
The treatment for rhabdomyosarcoma varies depending upon the location of tumor:[2]
Location | Symptoms |
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Head and neck | Wide local excision; chemotherapy +/- radiation therapy |
Bone around the eye | Biopsy; chemotherapy + radiation therapy |
Extremities | Wide local excision; resection of nearby lymph nodes; amputation for extensive tumors |
Abdomen or pelvis | Neoadjvant therapy with chemotherapy and radiotherapy; wide local excision |
Paratesticular region | Removal of testes and spermatic cord; ipsilateral retroperitoneal lymphnode resection |