Folate deficiency classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
There is no established system for the classification of Folate deficiency. However, it can be classified into different categories,based on the causative factors.
Classification
There is no established system for the classification of Folate deficiency. However, it can be classified as follows :
Some situations that increase the need for folate, may lead to folate deficiency in the body. These include:
- Hemorrhage
- Kidney dialysis
- Liver disease
- Malabsorption e.g. celiac disease
- Pregnancy and lactation
- Alcohol consumption
Medication induced Folate Deficiency:
Medications can interfere with folate utilization, including:
- Anticonvulsant medications e.g phenytoin
- Metformin
- Methotrexate, an anti-cancer drug also used as an anti-inflammatory
- Sulfasalazine, used in Inflammatory bowel syndrome
- Birth control pills
Genetic or Metabolic disorder:
- Defects in folate metabolism
- Defects in folate absorption
Dietary Deficiency:
- A diet low in fresh fruits, vegetables, and fortified cereals