Paget's disease of the breast MRI
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Differentiating Paget's disease of the breast from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
MRI may be performed to detect the breast cancer associated with Paget's disease of the breast.
MRI
- MRI may be performed to detect the breast cancer associated with Paget's disease of the breast.
- MRI is highly sensitive in the detection of clinically occult cancer with no mammographic and ultrasonographic signs of malignancy.
- MRI has a sensitivity of 95% compared to 70% of mammography in the detection of breast lesions.[1]
- MRI is useful not only to differentiate the normal nipple from the abnormal one but also to evaluate the extension of the tumor.
- It may show abnormal nipple enhancement, thickening of the nipple–areola complex.
- Even when clinically unsuspected it can show associated enhancment for DCIS or invasive tumor, or a combination of both[2][3][4][4].
References
- ↑ Gaspari, Eleonora; Ricci, Aurora; Liberto, Valeria; Scarano, Angela Lia; Fornari, Maria; Simonetti, Giovanni (2013). "An Unusual Case of Mammary Paget's Disease Diagnosed Using Dynamic Contrast-Enhanced MRI". Case Reports in Radiology. 2013: 1–5. doi:10.1155/2013/206235. ISSN 2090-6862.
- ↑ Frei KA, Bonel HM, Pelte MF, Hylton NM, Kinkel K (June 2005). "Paget disease of the breast: findings at magnetic resonance imaging and histopathologic correlation". Invest Radiol. 40 (6): 363–7. PMID 15905723.
- ↑ Morrogh M, Morris EA, Liberman L, Borgen PI, King TA (December 2007). "The predictive value of ductography and magnetic resonance imaging in the management of nipple discharge". Ann. Surg. Oncol. 14 (12): 3369–77. doi:10.1245/s10434-007-9530-5. PMID 17896158.
- ↑ 4.0 4.1 Amano G, Yajima M, Moroboshi Y, Kuriya Y, Ohuchi N (March 2005). "MRI accurately depicts underlying DCIS in a patient with Paget's disease of the breast without palpable mass and mammography findings". Jpn. J. Clin. Oncol. 35 (3): 149–53. doi:10.1093/jjco/hyi044. PMID 15741305.