Sexcord/ stromal ovarian tumors epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Epidemiology and Demographics

Incidence

Ovarian sex cord-stromal tumors are very uncommon neoplasms that represent only 7% of all ovarian tumors

Ovarian cancer incidence exhibits wide geographic variation.Reid BM, Permuth JB, Sellers TA. Epidemiology of ovarian cancer: a review. Cancer Biol Med. 2017;14(1):9–32. doi:10.20892/j.issn.2095-3941.2016.0084,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365187/

Prevalence

• The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
• In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
• The prevalence of [disease/malignancy] is estimated to be [number] cases annually.

Case-fatality rate/Mortality rate

• In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
• The case-fatality rate/mortality rate of [disease name] is approximately [number range].

Age

The age at presentation varies depending on the subtypes of sexcord-stromal ovarian tumors:

Fibromas:

• Although they can present at any age, the mean age of occurrence is in the late forties

Thecomas:

• They are more likely to occur in postmenopausal women

Sclerosing stromal tumor(SSTs):

• SSTs are more likely to occur in young women
• Approximately 80% of the reported cases are under 30 years of age
• A few cases have been reported in premenarchal girls, although SSTs most commonly occur after menarche

Steroid cell tumors:

• The average age of presentation is 43 years

Adult and juvenile granulosa cell tumors:

• The incidence of adult granulosa cell tumors peaks in early postmenopausal women
• The juvenile form occurs predominantly in children and young women (<30 years)

Race

• There is no racial predilection to [disease name].
• [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].

Gender

• [Disease name] affects men and women equally.
• [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.

Region

• The majority of [disease name] cases are reported in [geographical region].

• [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].