Hemophilia echocardiography and ultrasound
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]
Overview
There are no echocardiography findings associated with hemophilia. Ultrasound may be helpful in the diagnosis and follow-up of hemophilic arthropathy and in diagnosing massive intraabdominal bleeds. Findings on an ultrasound suggestive of hemophilic arthropathy inlcude soft-tissue changes, osteo-chondral changes, joint effusion, synovial hypertrophy, hemosiderin, and osteo-chondral abnormalities.
Echocardiography/Ultrasound
Echocardiography
There are no echocardiography findings associated with hemophilia.
Ultrasound
- Ultrasound may be helpful in the diagnosis and follow-up of hemophilic arthropathy and in diagnosing massive intraabdominal bleeds
- Ultrasound is highly reliable for assessing soft-tissue changes with an intraclass correlation coefficient (ICC) for specific joints given below:
- Ultrasound is substantially to highly reliable for assessing osteo-chondral changes with an intraclass correlation coefficient (ICC) for specific joints given below:
- It is highly sensitive (> 92%) for assessing synovial hypertrophy and hemosiderin in both ankles and knees[1]
- It has borderline sensitivity for detecting small amounts of fluid in ankles (70%) in contrast to knees (93%)
- It has variable sensitivity for evaluating osteo-chondral abnormalities (86-100% for ankles and 12-100% for knees)
References
- ↑ 1.0 1.1 1.2 Doria AS, Keshava SN, Mohanta A, Jarrin J, Blanchette V, Srivastava A, Moineddin R, Kavitha ML, Hilliard P, Poonnoose P, Gibikote S (March 2015). "Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation". AJR Am J Roentgenol. 204 (3): W336–47. doi:10.2214/AJR.14.12501. PMID 25714320.