Radiation proctitis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
- X- Ray was first discovered by Wilhelm Roentgen, in 1895
- In 1897, Walsh was the first to discover the association between Xray( Radiation) and the damaging effect on GIT tract in a person working with the radiation energy.He further reported the improvement in the symptoms if exposure being shielded by the lead.
- In 1942, the early and late intestinal effect of radiotherapy was first described by Warren and Friedman.
Historical Perspective
Discovery
- X- Ray was first discovered by Wilhelm Roentgen, in 1895
- In 1897, Walsh was the first to discover the association between Xray( Radiation) and the damaging effect on GIT tract in a person working with the radiation energy.He further reported the improvement in the symptoms if exposure being shielded by the lead.
- In 1912, Regaud et al. described the delayed effects on the irradiation in the small intestine of the dogs.[1]
- In 1917, the first case of the radiation enteritis being reported in a patient being treated for the malignant disease.
- In 1930, factitial proctitis was discovered in group of patient who had undergone the pelvic radiations by Buie.
- The early and late intestinal effect of radiotherapy was first described by Warren and Friedman in 1942.
- In 1976, Goldstein et al. observed clinical improvement of a patient with radiation-induced proctitis who received salicylazosulfapyridine in combination with prednisone.[2]
- In 1977, Pajares et al. also observed a decrease of rectal bleeding after administration of prednisone
- In 1984, Ben Bouali et al. demonstrated clinical and endoscopic improvement in 4 out of 33 patients treated with daily rectal administration of 5 mg of betamethasone in combination with diphenoxylate
- More recently, Triantafillidis et al. reported 5 patients treated for RP with enemas containing 5mg of betamethasone without any clinical improvement.
- In 1999, Kochhar et al. demonstrated that topical sucralfate produced sustained resolution of symptoms.
References
- ↑ Trzcinski, Radzislaw; Mik, Michal; Dziki, Lukasz; Dziki, Adam (2018). "Radiation Proctitis". doi:10.5772/intechopen.76200.
- ↑ Cotti, Guilherme; Seid, Victor; Araujo, Sérgio; Souza Jr., Afonso Henrique Silva e; Kiss, Desidério Roberto; Habr-Gama, Angelita (2003). "Conservative therapies for hemorrhagic radiation proctitis: a review". Revista do Hospital das Clínicas. 58 (5): 284–292. doi:10.1590/S0041-87812003000500008. ISSN 0041-8781.