Papillary thyroid cancer staging
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Papillary thyroid cancer Microchapters |
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Differentiating Papillary thyroid cancer from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Papillary thyroid cancer staging On the Web |
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American Roentgen Ray Society Images of Papillary thyroid cancer staging |
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Risk calculators and risk factors for Papillary thyroid cancer staging |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2] Sahar Memar Montazerin, M.D.[3]
Overview
According to the American Joint Committee on Cancer (AJCC) there are 4 stages of papillary thyroid cancer based on the clinical features and findings on imaging. Each stage is assigned a letter and a number that designate the tumor size, number of involved lymph node regions, and metastasis.
Staging
- According to the American Joint Committee on Cancer (AJCC) there are 4 stages of papillary thyroid cancer based on the clinical features and findings on imaging.[1]
- Each stage is assigned a letter and a number that designate the tumor size, number of involved lymph node regions, and metastasis.
| Primary tumor | |||
|---|---|---|---|
| Tumor size | Sub-stage | Finding | Image |
| T0 | No evidence of primary tumor | ||
| T1 | Tumor ≤2 cm in greatest dimension limited to the thyroid | ||
| T1 | a | Tumor ≤1 cm, limited to the thyroid |  |
| T1 | b | Tumor >1 cm but ≤2 cm in greatest dimension, limited to the thyroid |  |
| T2 | Tumor >2 cm but ≤4 cm in greatest dimension, limited to the thyroid | ||
| T3 | Tumor >4 cm in greatest dimension limited to the thyroid or any tumor with minimal extrathyroid extension (e.g., extension to sternothyroid muscle or peri-thyroid soft tissues) |  | |
| T4 | Advanced disease | ||
| T4 | a | Moderately advanced disease
Tumor of any size extending beyond the thyroid capsule to invade subcutaneous soft tissues, larynx, trachea, esophagus, or recurrent laryngeal nerve |
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| T4 | b | Very advanced disease
Tumor invades prevertebral fascia or encases carotid artery or mediastinal vessel |
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| TX | Primary tumor cannot be assessed | ||
| Regional lymph node involvement | |||
| Node involvement | Sub-stage | Finding | Image |
| N0 | No lymph node involvement | ||
| N1 | No regional lymph node metastasis | ||
| N1 | a | Metastases to Level VI (pretracheal, paratracheal, and prelaryngeal/Delphian lymph nodes) |  |
| N1 | b | Metastases to unilateral, bilateral, or contralateral cervical (Levels I, II, III, IV, or V) or retropharyngeal or superior mediastinal lymph nodes (Level VII) |  |
| NX | Regional lymph node cannot be assessed | ||
| Distant metastasis | |||
| Presence of metastasis | Sub-stage | Finding | Image |
| M0 | No distant metastasis | ||
| M1 | IV | Distant metastasis |  |
| Stage | T | N | M |
|---|---|---|---|
| Papillary thyroid carcinoma | |||
| YOUNGER THAN 55 YEARS | |||
| I | Any T | Any N | M0 |
| II | Any T | Any N | M1 |
| 55 YEARS AND OLDER | |||
| I | T1 | Any N | M0 |
| II | T1 | N1 | M0 |
| T2 | N1 | M0 | |
| T3a | Any N | M0 | |
| T3b | Any N | M0 | |
| III | T4a | Any N | M0 |
| IVA | T4b | Any N | M0 |
| IVB | Any T | Any N | M1 |
| T1 | N1 | M0 | |
| T2 | N1 | M0 | |
| T3a | N1 | M0 | |
| T3b | Any N | M0 | |
| T4 | Any N | M0 | |
| IVC | Any T | Any N | M1 |