Central pontine myelinolysis MRI
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]
Overview
MRI
Brain and spinal cord MRIs may be helpful in the diagnosis of Central pontine myelinolysis. Findings on MRI diagnostic of Central pontine myelinolysis include:[1][2]
- Symmetric signal intensity abnormality in the central pons at T2-weighted and FLAIR imaging
- This may progress to classic hyperintense “trident-shaped” central pontine abnormality, with sparing of the ventrolateral pons and corticospinal tracts
- Decreased T1 signal intensity
- Fluid attenuated inversion recovery (FLAIR) hyperintense lesion in the pons
- Intramedullary central T2 hyperintensity at axial T2W of spinal cord and sagittal T2W of thoracic spinal cord
References
- ↑ Ruzek KA, Campeau NG, Miller GM (2004). "Early diagnosis of central pontine myelinolysis with diffusion-weighted imaging". AJNR Am J Neuroradiol. 25 (2): 210–3. PMID 14970019.
- ↑ Jacob S, Gupta H, Nikolic D, Gundogdu B, Ong S (2014). "Central pontine and extrapontine myelinolysis: the great masquerader-an autopsy case report". Case Rep Neurol Med. 2014: 745347. doi:10.1155/2014/745347. PMC 3970353. PMID 24716023.