Pre-eclampsia causes
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Pre-eclampsia Microchapters |
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Pre-eclampsia causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Ogheneochuko Ajari, MB.BS, MS [3]
Overview
Common cause of preeclampsia include uteroplacental ischemia and genetic predisposition following
Causes
Common cause of preeclampsia include uteroplacental ischemia and genetic predisposition due to the following:[1][2]
- The formation of atheromatous plaques and fibrinoid necrosis of the spiral vessel walls
- Oxidative stress in trophoblast cells
- Apoptosis in trophoblast cells
- Systemic inflammatory response
- Vasospasm
- Platelet aggreggation
- Thrombin formation
- Deposition of the fibrin in multiple organs
References
- ↑ Lye, P.; Bloise, E.; Dunk, C.; Javam, M.; Gibb, W.; Lye, S.J.; Matthews, S.G. (2013). "Effect of oxygen on multidrug resistance in the first trimester human placenta". Placenta. 34 (9): 817–823. doi:10.1016/j.placenta.2013.05.010. ISSN 0143-4004.
- ↑ Mayrink, J.; Costa, M. L.; Cecatti, J. G. (2018). "Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction". The Scientific World Journal. 2018: 1–9. doi:10.1155/2018/6268276. ISSN 2356-6140.