Chorioamnionitis natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Adnan Ezici, M.D[2]
Overview
Natural History
The symptoms of chorioamnionitis usually develop during the pregnancy, and start with symptoms such as maternal fever, uterine tenderness, purulent/foul-smelling amniotic fluid, maternal/fetal tachycardia.[1]
- The most important clinical finding among patients with chorioamnionitis is fever, and temperature 100.4�F should be defined as abnormal during pregnancy.
- Although uterine tenderness is an important clinical finding, it might be challenging to differentiate uterine tenderness from the pain of the labor or conditions such as placental abruption. Also, the patient might not be able to feel the pain due to the effects of analgesics and anesthetic procedures.
- The presence of purulent/foul-smelling amniotic fluid depends on the responsible microorganism and the severity of the chorioamnionitis.
- Maternal tachycardia (>100 per minute) and fetal tachycardia (>160 per minute) are important and common clinical findings of chorioamnionitis.
- ↑ Tita AT, Andrews WW (June 2010). "Diagnosis and management of clinical chorioamnionitis". Clin Perinatol. 37 (2): 339–54. doi:10.1016/j.clp.2010.02.003. PMC 3008318. PMID 20569811.