Acrodermatitis chronica atrophicans laboratory findings
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2] Raviteja Guddeti, M.B.B.S. [3]
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Overview
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of acrodermatitis chronica atrophicans.
Laboratory Findings
- Physicians can use serologic and histologic examination to confirm the diagnosis of acrodermatitis chronica atrophicans.
- High anti-spirochetal antibody levels has been detected at indirect immunofluorescence and enzyme linked immunosorbent assay (ELISA).[1][2]
- Among various antigens in borrelia burgdorferi, flagellum antigen is one of the recommended serologic evaluation in acrodermatitis chronica atrophicans patients.[2]
- A study done on patients with acrodermatitis chronica atrophicans revealed rheumatoid factor in 32% of patients.[2]
- Biopsy shows chronic inflammatory signs in chronic cases. Other histological finding are listed below: [3][1]
References
- ↑ 1.0 1.1 Asbrink E, Hovmark A, Olsson I (1986). "Clinical manifestations of acrodermatitis chronica atrophicans in 50 Swedish patients". Zentralbl Bakteriol Mikrobiol Hyg A. 263 (1–2): 253–61. doi:10.1016/s0176-6724(86)80128-6. PMID 3577484.
- ↑ 2.0 2.1 2.2 Hansen K, Asbrink E (1989). "Serodiagnosis of erythema migrans and acrodermatitis chronica atrophicans by the Borrelia burgdorferi flagellum enzyme-linked immunosorbent assay". J Clin Microbiol. 27 (3): 545–51. doi:10.1128/jcm.27.3.545-551.1989. PMC 267355. PMID 2715325.
- ↑ Rosenlund S, Bækgaard N, Menné T (2011). "[Acrodermatitis chronica atrophicans can be difficult to diagnose]". Ugeskr. Laeg. (in Danish). 173 (50): 3272–3. PMID 22153213. Unknown parameter
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