Lactic acidosis differential diagnosis
Lactic acidosis should be differentiated from:
- Any shock state
- SIRS; lactate may be 2-5 mEq/L
- Thiamine deficiency
- Seizures
- Infarcted colon
- Hepatic failure
- Malignancy
- Heavy exercise
- Albuterol and other beta agonists
- Toxicologic Causes:
- Cyanide
- Carbon Monoxide
- Metformin use in diabetics
- Didanosine
- Stavudine
- Zidovudine
- Linezolid
- Strychnine
- Rotenone (Fish Poison
- Phospine (rodenticide)
- INH (if patient seizes)
- Valproate
- Hydrogen Sulfide
- Nitroprusside (cyanide)
- Ricin & Castor Beans
- Propofol
- Sympathomimetics (cocaine, methamphetamine)
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