Acute disseminated encephalomyelitis historical perspective
|
Acute disseminated encephalomyelitis Microchapters |
|
Differentiating Acute disseminated encephalomyelitis from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Acute disseminated encephalomyelitis historical perspective On the Web |
|
American Roentgen Ray Society Images of Acute disseminated encephalomyelitis historical perspective |
|
FDA on Acute disseminated encephalomyelitis historical perspective |
|
CDC on Acute disseminated encephalomyelitis historical perspective |
|
Acute disseminated encephalomyelitis historical perspective in the news |
|
Blogs on Acute disseminated encephalomyelitis historical perspective |
|
Directions to Hospitals Treating Acute disseminated encephalomyelitis |
|
Risk calculators and risk factors for Acute disseminated encephalomyelitis historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Please help WikiDoc by adding content here. It's easy! Click here to learn about editing.
Overview
Historical Perspective
- Acute disseminated encephalomyelitis has experimental evidence suggests that both primary autoimmune responses and immunological responses triggered by infection may play a role in central nervous system inflammation and demyelination. Clinically and histopathologically, two animal models closely resemble.
- To begin, experimental autoimmune encephalomyelitis (EAE) is commonly utilized to investigate the underlying disease processes, after immunization with CNS homogenate or encephalitogenic myelin peptides emulsified in Freund complete adjuvant. Inflammatory demyelinating lesions can be seen histopathologically in the brains and spinal cords of affected animals.
- Theiler murine encephalomyelitis, which was first utilized as an animal model in the 1930s, has been used to investigate infectious and parainfectious pathways that may play a role in disease etiology.