Acute disseminated encephalomyelitis natural history, complications and prognosis
|
Acute disseminated encephalomyelitis Microchapters |
|
Differentiating Acute disseminated encephalomyelitis from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Acute disseminated encephalomyelitis natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Acute disseminated encephalomyelitis natural history, complications and prognosis |
|
FDA on Acute disseminated encephalomyelitis natural history, complications and prognosis |
|
CDC on Acute disseminated encephalomyelitis natural history, complications and prognosis |
|
Acute disseminated encephalomyelitis natural history, complications and prognosis in the news |
|
Blogs on Acute disseminated encephalomyelitis natural history, complications and prognosis |
|
Directions to Hospitals Treating Acute disseminated encephalomyelitis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sujaya Chattopadhyay, M.D.[2]
Overview
Natural History
- The classic form, accounting for 70-90% of cases, typically follows a monophasic pattern[1][2]. However, multiphasic disease progression (M-ADEM) has also been previously reported.
- The lag period between onset to first relapse can vary from 2 months to 8 years, with one case showing recurrence after three decades.
- Most of M-ADEM patients demonstrate resolution of lesions with no neurological sequelae on long-term clinical and imaging follow-up.
- MRI of patients with co-existent M-ADEM and anti-MOG antibodies typically reveal no new lesions in the asymptomatic period.
Complications
Prognosis
References
- ↑ Leake JA, Albani S, Kao AS, Senac MO, Billman GF, Nespeca MP; et al. (2004). "Acute disseminated encephalomyelitis in childhood: epidemiologic, clinical and laboratory features". Pediatr Infect Dis J. 23 (8): 756–64. doi:10.1097/01.inf.0000133048.75452.dd. PMID 15295226.
- ↑ Tenembaum S, Chamoles N, Fejerman N (2002). "Acute disseminated encephalomyelitis: a long-term follow-up study of 84 pediatric patients". Neurology. 59 (8): 1224–31. doi:10.1212/wnl.59.8.1224. PMID 12391351.