Anasarca
| Anasarca | |
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| ICD-10 | R60.1 |
| ICD-9 | 782.3 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Anasarca (or "extreme generalized edema") is a medical symptom characterized by widespread swelling of the skin due to effusion of fluid into the extracellular space.
A good mnemonic for anasarka is: Anasarka is like a parka, all over.
It is usually caused by either congestive cardiac failure, liver failure (cirrhosis of the liver) or renal failure/disease.
It can also be created from the administration of exogenous intravenous fluid.
Certain plant-derived anticancer chemotherapeutic agents, such as docetaxel, cause anasarca through a poorly understood capillary leak syndrome.
This symptom is also called leucophlegmatia.
Complete Differential Diagnosis of the Causes of Anasarca:
(In alphabetical order)
- Acute renal failure
- Allergic reactions
- Angioedema
- Burns
- Calcium channel blockers
- Capillary leak syndrome
- Cardiac tamponade
- Chronic kidney disease
- Constrictive pericarditis
- Cor pulmonale
- Diazoxide
- Dilated cardiomyopathy
- Docetaxel
- Eclampsia
- Effusive-constrictive pericarditis
- Estrogens
- Fludrocortisone
- Glomerulonephritis
- Haemolytic disease of the newborn
- Heart failure
- Hepatic cirrhosis
- Hereditary angioedema
- Hypertrophic cardiomyopathy
- Hypoalbuminemia
- Hypoproteinemia
- Hypothyroidism
- Idiopathic edema
- Increased capillary permeability
- Increased interstitial oncotic pressure
- Interleukin-2 therapy
- Kwashiorkor
- Lymphatic obstruction
- Malnutrition
- Malignant ascites
- Minoxidil
- Nephrotic syndrome
- Nodal enlargement due to malignancy
- Nonsteroidal antiinflammatory drugs
- Ovarian hyperstimulation syndrome
- POEMS syndrome
- Portal thrombosis
- Postmastectomy
- Pramipexole
- Pregnancy
- Protein loss
- Protein-losing enteropathy
- Reduced albumin synthesis
- Refeeding edema
- Restrictive cardiomyopathy
- Severe inflammation or sepsis
- Sodium overload
- Thiazolidinediones
- Trauma
- Tricuspid stenosis
- Tropical sprue
- Venous obstruction
- Water overload
- Yellow nail syndrome
Complete Differential Diagnosis of the Causes of Anasarca:
(By organ system)
| Cardiovascular | Cardiac tamponade ,
Constrictive pericarditis, Cor pulmonale, Dilated cardiomyopathy, Effusive-constrictive pericarditis, Heart failure, Hypertrophic cardiomyopathy, Restrictive cardiomyopathy, Tricuspid stenosis |
| Chemical / poisoning | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | Calcium channel blockers, Diazoxide, Docetaxel, Estrogens
Fludrocortisone, Interleukin-2 therapy, Minoxidil, Nonsteroidal antiinflammatory drugs |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | No underlying causes |
| Gastroenterologic | Alcoholic liver disease , Autoimmune hepatitis, [[Chronic hepatitis B], Chronic hepatitis C, Hepatic cirrhosis, Hepatic venous obstruction, Hereditary hemochromatosis, Portal thrombosis, Primary biliary cirrhosis, Primary sclerosing cholangitis, Wilson's disease |
| Genetic | Angioedema, Alpha-1-antitrypsin deficiency, Hereditary angioedema
Hereditary hemochromatosis, Hypertrophic cardiomyopathy, Wilson's disease, Yellow nail syndrome |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | Tropical sprue |
| Musculoskeletal / Ortho | No underlying causes |
| Neurologic | No underlying causes |
| Nutritional / Metabolic | Hypoalbuminemia, Hypoproteinaemia, Kwashiorkor, Malnutrition
Protein loss, Protein-losing enteropathy, Reduced albumin synthesis, Refeeding edema, Sodium overload, Tropical sprue, Water overload |
| Obstetric/Gynecologic | Eclampsia, Estrogens, Haemolytic disease of the newborn, Ovarian hyperstimulation syndrome, Pregnancy |
| Oncologic | Malignant ascites |
| Opthalmologic | No underlying causes |
| Overdose / Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal / Electrolyte | No underlying causes |
| Rheum / Immune / Allergy | Haemolytic disease of the newborn, Autoimmune hepatitis |
| Sexual | No underlying causes |
| Trauma | Trauma |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
Template:Skin and subcutaneous tissue symptoms and signs Template:Nervous and musculoskeletal system symptoms and signs Template:Urinary system symptoms and signs Template:Cognition, perception, emotional state and behaviour symptoms and signs Template:Speech and voice symptoms and signs Template:General symptoms and signs
Template:WH Template:WS Johnfanisrour 20:17, 15 January 2009 (UTC)John Fani SrourJohnfanisrour 20:17, 15 January 2009 (UTC)