Congestive heart failure risk factors
Heart failure | |
ICD-10 | I50.0 |
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ICD-9 | 428.0 |
DiseasesDB | 16209 |
MedlinePlus | 000158 |
eMedicine | med/3552 |
MeSH | D006333 |
Cardiology Network |
Discuss Congestive heart failure risk factors further in the WikiDoc Cardiology Network |
Adult Congenital |
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Biomarkers |
Cardiac Rehabilitation |
Congestive Heart Failure |
CT Angiography |
Echocardiography |
Electrophysiology |
Cardiology General |
Genetics |
Health Economics |
Hypertension |
Interventional Cardiology |
MRI |
Nuclear Cardiology |
Peripheral Arterial Disease |
Prevention |
Public Policy |
Pulmonary Embolism |
Stable Angina |
Valvular Heart Disease |
Vascular Medicine |
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Risk Factors for the Development of Heart Failure
- Demographic factors
- Age
- Gender
- Low socioeconomic status
- Lifestyle-related factors
- Tobacco and coffee consumption
- Alcohol consumption
- Dietary sodium intake
- Recreational drug use: Cocaine, methamphetamines.
- Comorbidities
- Echocardiographic factors
- Ventricular dimension
- Ventricular mass
- Diastolic filling impairment
- Pharmacological factors
- Chemotherapeutic agents
- Non-steroidal anti-inflammatory drugs
- Thiazolidinediones?
- Doxazosin
- Biochemical
- Albuminuria
- Homocysteine: Elevated plasma homocysteine levels are associated with almost a 75% increase in risk for heart failure development.
- Tumor necrosis factor-alpha (TNF-alpha): After adjustment for other risk factors, every tertile increment in tumor necrosis factor-alpha (TNF-alpha) levels was associated with a 60% increase in risk of heart failure. TNF-alpha has several negative pleiotropic effects and also negative inotropic properties that may be responsible for excessive heart failure risk. TNF-alpha is also associated with progression of heart failure.
- Interleukin-6: IL-6 is a pro-inflammatory cytokine which associated with an excessive risk of development of heart failure.
- C-reactive protein
- Insulin-like growth factor-I (IGF-I)
- Natriuretic peptides
- Genetic risk factors
Risk Factors Associated with Heart Failure Progression and Outcomes
- Clinical
- Etiology
- Age
- Gender
- Symptom duration
- NYHA class
- Weight
- Heart rate
- Mean arterial pressure
- S3 gallop
- Jugular venous pressure
- Cardiothoracic ratio
- Renal function
- Serum sodium
- Troponin T
- History of diabetes
- Anemia
- Echocardiographic
- Ejection fraction
- Exercise ejection fraction
- Ventricular dimensions
- Sphericity index
- Prolonged isovolumic relaxation
- Restrictive mitral filling
- Changes in E/A ratio
- Mitral regurgitation
- Contractile reserve
- Left ventricular mass
- Exercise Tolerance
- Exercise duration
- Peak O2 consumption
- VE/VCO2
- Anaerobic threshold 6-minute walk test
- Hemodynamics
- Cardiac index
- Pulmonary artery pressure
- Pulmonary artery wedge pressure
- Pulmonary vascular resistance
- Stroke work index
- Right atrial pressure
- A-V oxygen difference
- Coronary sinus O2 content
- Electrophysiological
- Conduction delay
- Atrial arrhythmia
- Family history of sudden death
- Presence of late potentials
- QT dispersion
- T wave alternans
- Neurohormonal
- Renin-angiotensin system
- Angiotensin II
- Aldosterone
- Plasma renin activity
- Sympathetic nervous system
- Norepinephrine
- Epinephrine
- Heart rate variability
- Norepinephrine spillover
- Natriuretic factors
- Atrial natriuretic peptide
- B-type natriuretic peptide
- N-terminal-pro-ANP
- Cytokines and others