Patent ductus arteriosus medical therapy in term and older children

Patent Ductus Arteriosus Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Associate Editor-In-Chief:Cafer Zorkun, M.D., Ph.D. [2]; Keri Shafer, M.D. [3] Priyamvada Singh, MBBS [[4]]

Assistant Editor-In-Chief: Kristin Feeney, B.S. [[5]]

In term infants and older patients, the ProstaglandinE2 inhibitors (indomethacin and ibuprofen)have not shown to be effective. This is so because the ductus in premature baby is different histologicaly from in older patients. As a result, pharmacologic therapy is only used routinely in preterm infants.