Noncompaction cardiomyopathy biopsy
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Noncompaction Cardiomyopathy Microchapters |
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Pathophysiology |
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Differentiating Noncompaction Cardiomyopathy from other Diseases |
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Diagnosis |
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Treatment |
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Noncompaction cardiomyopathy biopsy On the Web |
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Risk calculators and risk factors for Noncompaction cardiomyopathy biopsy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Both skeletal and cardiac biopsies may reveal abnormal histologic findings.
Skeletal Biopsy
A skeletal biopsy can be performed which may demonstrate inclusion bodies or myopathic changes [1].
Cardiac Biopsy
- Interstitial fibrosis was observed in 5/5 patients with isolated noncompaction cardiomyopathy who underwent right ventricular biopsy[2]
- Endomyocardial thickening and subendocardial fibroelastosis was observed in 3/5 patients who underwent right ventricular biopsy.
- Myocyte necrosis has been observed in areas of trabeculation [3][4].
References
- ↑ Botto, LD. Left ventricular noncompaction. Orphanet encyclopedia. http://www.orpha.net/data/patho/GB/uk-LVNC.pdf
- ↑ Hamamichi Y, Ichida F, Hashimoto I, et al. Isolated noncompaction of the ventricular myocardium: ultrafast computer tomography and magnetic resonance imaging. Int J Cardiovasc Imaging. 2001; 17: 305–314.
- ↑ Oechslin EN, Attenhofer Jost CH, Rojas JR, et al. Long-term follow-up of 34 adults with isolated left ventricular noncompaction: a distinct cardiomyopathy with poor prognosis. J Am Coll Cardiol. 2000; 36: 493–500.
- ↑ Finsterer J, Stollberger C, Feichtinger H. Histological appearance of left ventricular hypertrabeculation/noncompaction. Cardiology. 2002; 98: 162–164.