Hitachimycin

Hitachimycin

File:Hitachimycin.png
Identifiers
IUPAC name (2Z,4E,6E,12E)-16,20-dihydroxy-21-methoxy- 3-methyl-10-phenyl-9-azabicyclo[17.3.0] docosa-2,4,6,12,19-pentaene-8,18-dione
CAS Number	77642-19-4
PubChem CID	5384563
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C29H35NO5
Molar mass	477.592 g/mol

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Hitachimycin, also known as stubomycin, is a cyclic polypeptide produced by Streptomyces that acts as an antibiotic. It exhibits cytotoxic activity against mammalian cells, Gram-positive bacteria, yeast, and fungi, as well as hemolytic activity; this is mediated by changes at the cell membrane and subsequent lysis. Owing to its cytotoxic activity against mammalian cells and tumors, it was first proposed as a antitumor antibiotic.

As of 2007, it has not been used in a clinical setting.