Atrial fibrillation causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The most common cause of atrial fibrillation is atrial dilation associated with hypertension. Approximately 1/3 of patients have familial atrial fibrillation which is due to an underlying genetic disorder. Given the number of patients who undergo coronary artery bypass grafting in the developed world, this is an increasing underlying cause of atrial fibrillation. Other general causes include the advancing age of the population this hemodynamic stress of heart failure and valvular heart disease, myocardial ischemia, a variety of inflammatory disorders, pulmonary diseases, alcohol and drug abuse, and endocrine disorders.
Differential Diagnosis of the Underlying Causes of Atrial Fibrillation
(By organ system)
Cardiovascular | Atrial ischemia or atrial infarction, Atrial myxoma, Atrial septal defect, Cardiac tumors, Cardiomyopathy, Channelopaties particularly abnormalities in the sodium channels |
Chemical / poisoning | Alcohol, Alcohol withdrawal, Breath spray which contains alcohol [1], Caffeine |
Dermatologic | No underlying causes |
Drug Side Effect | No underlying causes |
Ear Nose Throat | No underlying causes |
Endocrine | No underlying causes |
Environmental | No underlying causes |
Gastroenterologic | No underlying causes |
Genetic | Atherosclerosis, Channelopaties particularly abnormalities in the sodium channels |
Hematologic | No underlying causes |
Iatrogenic | No underlying causes |
Infectious Disease | No underlying causes |
Musculoskeletal / Ortho | No underlying causes |
Neurologic | No underlying causes |
Nutritional / Metabolic | Atherosclerosis |
Obstetric/Gynecologic | No underlying causes |
Oncologic | Atrial myxoma, Bronchogenic carcinoma, Cardiac tumors |
Opthalmologic | No underlying causes |
Overdose / Toxicity | Alcohol, Alcohol withdrawal, Breath spray which contains alcohol [1], Caffeine |
Psychiatric | No underlying causes |
Pulmonary | Bronchogenic carcinoma |
Renal / Electrolyte | No underlying causes |
Rheum / Immune / Allergy | No underlying causes |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | Channelopaties particularly abnormalities in the sodium channels |
Complete List of Underlying Causes of Atrial Fibrillation
(in alphabetical order)
- Age increase. 4% of those over 60 years and 8% of those over 80 years of age have atrial fibrillation.
- Alcohol and alcohol withdrawal
- Atherosclerosis
- Atrial ischemia or atrial infarction
- Atrial myxoma
- Atrial septal defect
- Breath spray which contains alcohol [1]
- Bronchogenic carcinoma
- Caffeine
- Cardiac tumors
- Cardiomyopathy
- Channelopaties particularly abnormalities in the sodium channels
- Cocaine
- Coffee
- Collagen vascular disease
- Congestive heart failure
- Constrictive pericarditis
- Conivaptan
- Coronary Artery Bypass Graft Surgery
- Coronary Artery Disease
- Diabetes
- Dilated cardiomyopathy
- Endocarditis
- Esophageal surgery
- Ethanol
- Familial atrial fibrillation type 1
- Familial atrial fibrillation type 3
- Genetics
- HOCM
- Hypertension
- Hyperthyroidism
- Hypothermia
- Hypothyroidism
- Hypoxia
- Interleukin 11
- Left ventricular hypertrophy
- Lung cancer
- Lutembacher syndrome
- Methamphetamines
- Mitral regurgitation
- Mitral stenosis
- Myocardial infarction
- Myocarditis
- Obesity
- Pericarditis and pericardial disease in general
- Pheochromocytoma
- Pneumonia
- Porfimer
- Pulmonary embolism
- Pulmonary hypertension
- Rheumatic fever
- Sarcoidosis
- ST elevation myocardial infarction (STEMI)
- Stimulants
- Stroke
- Subarachnoid hemorrhage
- Tea
- Tricuspid regurgitation
- Tricuspid stenosis
- unstable angina
- Valvular heart disease
Loan Atrial Fibrillation
In about 10% of patients no underlying cause is identified. This condition is called lone atrial fibrillation.