Klinefelter's syndrome laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Laboratory Findings

A karyotype is used to confirm the diagnosis. In this procedure, a small blood sample is drawn. White blood cells are then separated from the sample, mixed with tissue culture medium, incubated, and checked for chromosomal abnormalities, such as an extra X chromosome.

The following tests may be performed:

• Semen count
• Serum estradiol levels (a type of estrogen)
• Serum follicle stimulating hormone
• Serum luteinizing hormone
• Serum testosterone