SMARCD3

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
Identifiers
Symbols	SMARCD3 ; Rsc6p; BAF60C; CRACD3; MGC111010
External IDs	Template:OMIM5 Template:MGI HomoloGene: 2314
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SMARCD3 204099 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3, also known as SMARCD3, is a human gene.

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Further reading

• Wang W, Xue Y, Zhou S; et al. (1996). "Diversity and specialization of mammalian SWI/SNF complexes". Genes Dev. 10 (17): 2117–30. PMID 8804307.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang W, Côté J, Xue Y; et al. (1996). "Purification and biochemical heterogeneity of the mammalian SWI-SNF complex". EMBO J. 15 (19): 5370–82. PMID 8895581.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ring HZ, Vameghi-Meyers V, Wang W; et al. (1998). "Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome". Genomics. 51 (1): 140–3. doi:10.1006/geno.1998.5343. PMID 9693044.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Shanahan F, Seghezzi W, Parry D; et al. (1999). "Cyclin E associates with BAF155 and BRG1, components of the mammalian SWI-SNF complex, and alters the ability of BRG1 to induce growth arrest". Mol. Cell. Biol. 19 (2): 1460–9. PMID 9891079.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Barker N, Hurlstone A, Musisi H; et al. (2001). "The chromatin remodelling factor Brg-1 interacts with beta-catenin to promote target gene activation". EMBO J. 20 (17): 4935–43. doi:10.1093/emboj/20.17.4935. PMID 11532957.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Otsuki T, Furukawa Y, Ikeda K; et al. (2002). "Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex". Hum. Mol. Genet. 10 (23): 2651–60. PMID 11726552.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Scherer SW, Cheung J, MacDonald JR; et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. doi:10.1126/science.1083423. PMID 12690205.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hillier LW, Fulton RS, Fulton LA; et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nagaraja GM, Kandpal RP (2004). "Chromosome 13q12 encoded Rho GTPase activating protein suppresses growth of breast carcinoma cells, and yeast two-hybrid screen shows its interaction with several proteins". Biochem. Biophys. Res. Commun. 313 (3): 654–65. PMID 14697242.
• Debril MB, Gelman L, Fayard E; et al. (2004). "Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit". J. Biol. Chem. 279 (16): 16677–86. doi:10.1074/jbc.M312288200. PMID 14701856.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mahmoudi T, Parra M, Vries RG; et al. (2006). "The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter". J. Biol. Chem. 281 (29): 19960–8. doi:10.1074/jbc.M603336200. PMID 16687403.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Olsen JV, Blagoev B, Gnad F; et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)