Cavernous sinus thrombosis natural history, complications and prognosis

Cavernous sinus thrombosis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Natural History

In reality, most patients with cavernous sinus thrombosis do not present with such serious illness, and if they survive tend to have a better prognosis than patients with arterial thrombosis. The real trick is suspecting and making the diagnosis.

Complications

Progressive coma and death with hemorrhagic infarction pathologically.

Prognosis

• Prognosis better as diagnosis is increasing made with imaging instead of autopsy, with mortality rates down from 100% to 6.5% in a recent review of 76 patients.
• Poor prognostic features:

  • Rapid progression
  • Coma
  • Extremes of age
  • Focal signs and symptoms
  • Hemorrhagic infarct
  • Serious underlying cause

• Of note, if patient survives, outcome is better than for arterial infarct

References

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