Focal segmental glomerulosclerosis overview
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Focal segmental glomerulosclerosis Microchapters |
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Differentiating Focal segmental glomerulosclerosis from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Focal segmental glomerulosclerosis overview On the Web |
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American Roentgen Ray Society Images of Focal segmental glomerulosclerosis overview |
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Directions to Hospitals Treating Focal segmental glomerulosclerosis |
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Risk calculators and risk factors for Focal segmental glomerulosclerosis overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief:’’’ Cafer Zorkun, M.D., Ph.D. [2]
Overview
Focal segmental glomerulosclerosis (FSGS) is a cause of nephrotic syndrome in children and adolescents, as well as an important cause of kidney failure in adults.[1] Minimal change disease (MCD) is by far the most common cause of nephrotic syndrome in children: MCD and primary FSGS may have a similar cause.[1]
The individual components of the name refer to the appearance of the kidney tissue on biopsy: focal - only some of the glomeruli are involved (as opposed to diffuse), segmental - only part of an entire glomerulus is involved (as opposed to global), glomerulosclerosis - refers to scarring of the glomerulus (a part of the nephron (the functional unit of the kidney)).