Focal segmental glomerulosclerosis classification
Focal segmental glomerulosclerosis Microchapters |
Differentiating Focal segmental glomerulosclerosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief:’’’ Cafer Zorkun, M.D., Ph.D. [2]
Overview
Classification
Depending on the cause it is broadly classified as
- Primary, when no underlying cause is found; usually presents as nephrotic syndrome
- Secondary, when an underlying cause is identified; usually presents with kidney failure and proteinuria. This is actually a heterogeneous group including a myriad causes such as
- Infections such as HIV (known as HIV-Associated Nephropathy)
- Toxins and drugs such as heroin and pamidronate
- Familial forms
- Secondary to nephron loss and hyperfiltration, such as with chronic pyelonephritis and reflux, morbid obesity, diabetes mellitus