Aortic stenosis echocardiography

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Aortic Stenosis Microchapters

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Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Aortic Stenosis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Cardiac Stress Test

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography

Cardiac Catheterization

Aortic Valve Area

Aortic Valve Area Calculation

Treatment

General Approach

Medical Therapy

Surgery

Percutaneous Aortic Balloon Valvotomy (PABV) or Aortic Valvuloplasty

Transcatheter Aortic Valve Replacement (TAVR)

TAVR vs SAVR
Critical Pathway
Patient Selection
Imaging
Evaluation
Valve Types
TAVR Procedure
Post TAVR management
AHA/ACC Guideline Recommendations

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Prevention

Precautions and Prophylaxis

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Mohammed A. Sbeih, M.D. [2]; Lakshmi Gopalakrishnan, M.B.B.S. [3]

Overview

Echocardiography is the best non-invasive test to evaluate the aortic valve anatomy and function. Echocardiography can be used to estimate the gradient across the aortic valve using the modified Bernoulli equation (gradient = 4 X velocity2). The flow must be constant, so as the velocity increases, the valve area decreases proportionally. Echocardiography can also be used to assess the severity of left ventricular hypertrophy.

Optimal Echocardiography Views

Parasternal Long Axis View

The parasternal long axis view visualizes the right and non coronary leaflets.

Parasternal Short Axis View

In the parasternal short axis view, the aortic leaflets open equally and form a circular orifice during systole. During diastole, the normal leaflets form a three pointed star with prominence at the closing point (nodules of Arentius).

Severity of Aortic Stenosis

Aortic stenosis severity can be assessed by estimating both the pressure gradient across the valve and the aortic valve area.

  • Using the velocity of the blood through the valve, the pressure gradient across the valve can be calculated by the equation:

    Gradient = 4(velocity)² mmHg

Normal Aortic Valve:

  • A normal aortic valve has no gradient, and
  • Aortic valve surface area is of 2.5 to 3.5 cms2.

Mild Aortic Stenosis:

  • Mean pressure gradient across the valve is less than 25 mm Hg, or
  • Valve surface area is between 1.5 and 2.5 cms2, or
  • Jet velocity less than 3.0 m per second

Moderate Aortic Stenosis:

  • Mean pressure gradient across the valve is between 25 mm Hg and 40 mm Hg, or
  • Valve surface area is between 1.0 and 1.5 cms2, or
  • Jet velocity 3.0 to 4.0 m per second

Moderate to Severe Aortic Stenosis

  • Valve surface area is between 0.7 and 1.0 cms2

Severe Aortic Stenosis:

  • Mean pressure gradient across the valve is more than 40 mm Hg, or
  • Valve surface area is less than 0.7 cm2, or
  • Jet velocity is greater than 4.0 m per second


Severity mild moderate severe
Valve Surface Area 2.5 - 1.5 1.5 - 1.0 <1.0
Jet Velocity (m/s) 2 - 3 3 - 4 >4
Peak Gradient (mmHg) <25 25 - 40 >40
Mean Gradient (mmHg) <20 20-40 >40

ACC/AHA Guidelines- Echocardiography (Imaging, Spectral, and Color Doppler) in Aortic Stenosis [1]

Class I
"1.Echocardiography is recommended for the diagnosis and assessment of aortic stenosis severity.(Level of Evidence: B) "
"2.Echocardiography is recommended in patients with aortic stenosis for the assessment of left ventricular wall thickness, size, and function.(Level of Evidence: C) "
"3.Echocardiography is recommended for re-evaluation of patients with known aortic stenosis and changing symptoms or signs.(Level of Evidence: B) "
"4.Echocardiography is recommended for the assessment of changes in hemodynamic severity and left ventricular function in patients with known aortic stenosis during pregnancy. (Level of Evidence: B) "
"5.Transthoracic echocardiography is recommended for re-evaluation of asymptomatic patients: every year for severe aortic stenosis; every 1 to 2 years for moderate aortic stenosis; and every 3 to 5 years for mild aortic stenosis.(Level of Evidence: C) "


Class IIa

1. Dobutamine stress echocardiography is reasonable to evaluate patients with low-flow/low-gradient aortic stenosis and left ventricular dysfunction. (Level of Evidence: B)}}

Examples

Demonstration of Diastolic Mitral Regurgitation due to Severe Aortic Stenosis
Diastolic mitral regurgitation due to severe aortic stenosis
Diastolic mitral regurgitation due to severe aortic stenosis


Demonstration of Aortic regurgitation combined with Aortic Stenosis

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Demonstration of Calcific Aortic Stenosis with Mitral Annular Calcification and Moderate Mitral Regurgitation

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Low flow Aortic Stenosis

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Severe Aortic Stenosis without Aortic Regurgitation

Cntinuous wave doppler below shows a peak velocity across the aortic valve of a gradient of 85 mmHg, which is compatible with severe aortic stenosis. No aortic regurgitation is present.


References

  1. Bonow RO, Carabello BA, Chatterjee K, de Leon AC, Faxon DP, Freed MD; et al. (2008). "2008 focused update incorporated into the ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to revise the 1998 guidelines for the management of patients with valvular heart disease). Endorsed by the Society of Cardiovascular Anesthesiologists, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons". J Am Coll Cardiol. 52 (13): e1–142. doi:10.1016/j.jacc.2008.05.007. PMID 18848134.

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