Peripheral arterial disease epidemiology and demographics
Editors-in-Chief: C. Michael Gibson; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [1]
Overview
The prevalence of peripheral arterial disease in the general population is 12–14%. Peripheral arterial disease is even more common among the elderly and affects up to 20% of patients over the age of 70 years [1]. Peripheral vascular disease affects 1 in 3 diabetics over the age of 50. Approximately 10 million Americans have peripheral arterial disease.
Age
- The incidence of peripheral arterial disease increases with increasing age[2]
- The incidence of symptomatic PVD increases with age, from about 0.3% per year for men aged 40–55 years to about 1% per year for men aged over 75 years.
The Diabetes Control and Complications Trial and U.K. Prospective Diabetes Study trials in people with type 1 and type 2 diabetes, respectively, demonstrated that glycemic control is more strongly associated with microvascular disease than macrovascular disease. It may be that pathologic changes occurring in small vessels are more sensitive to chronically elevated glucose levels than is atherosclerosis occurring in larger arteries.[3]
References
- ↑ Shammas NW (2007). "Epidemiology, classification, and modifiable risk factors of peripheral arterial disease". Vascular Health and Risk Management. 3 (2): 229–34. PMC 1994028. PMID 17580733.
- ↑ "Peripheral arterial disease prevention and prevalence". Peripheral Arterial Disease. 2007. Retrieved 2007-12-03. Unknown parameter
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