Gout risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Several factors may put a person at risk for developing gout. These include the presence of; hypertension, diabetes, hypercholesterolemia, obesity, and alcohol abuse. Certain medications may also put a person at a higher risk for developing gout.
Risk Factors
- Hypertension
- Diabetes
- Hypercholesterolemia
- Overweight
- Alcohol abuse- Alcohol intake often causes acute attacks of gout and hereditary factors may contribute to the elevation of uric acid.
- Foods that are rich in purines, such as salmon, sardines, organ meats, asparagus, mushrooms and herring.
- Medications such as hydrochlorothiazide, niacin, aspirin, cyclosporine, pyrazinamide and ethambutol, and some drugs used to treat cancer.
- Family history of gout
- Male, or female after menopause
A seasonal link also may exist, with significantly higher incidence of acute gout attacks occurring in the spring.[1] [2]
Gout also can develop as co-morbidity of other diseases, including polycythaemia, leukaemia, intake of cytotoxics, obesity, diabetes, hypertension, renal disorders, and hemolytic anemia. This form of gout is often called secondary gout. Diuretics (particularly thiazide diuretics) have traditionally been blamed for precipitating attacks of gout, but a Dutch case-control study from 2006 appears to cast doubt on this conclusion.[3]
References
- ↑ Schlesinger N, Gowin KM, Baker DG, Beutler AM, Hoffman BI, Schumacher HR Jr. "Acute gouty arthritis is seasonal". Retrieved 2007-09-27.
- ↑ Gallerani M, Govoni M, Mucinelli M, Bigoni M, Trotta F, Manfredini R. "Seasonal variation in the onset of acute microcrystalline arthritis". Retrieved 2007-09-27.
- ↑ Janssens H, van de Lisdonk E, Janssen M, van den Hoogen H, Verbeek A (2006). "Gout, not induced by diuretics? A case-control study from primary care". Ann Rheum Dis. 65 (8): 1080&ndash, 3. doi:10.1136/ard.2005.040360. PMID 16291814.