Non-Polio enterovirus infections natural history, complications and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History, Complications and Prognosis
Most people who are infected with a non-polio enterovirus have no disease at all. Infected persons who become ill usually develop either mild upper respiratory symptoms (a "summer cold"), a flu-like illness with fever and muscle aches, or an illness with rash. Less commonly, some persons have "aseptic" or viral meningitis. Rarely, a person may develop an illness that affects the heart (myocarditis) or the brain (encephalitis) or causes paralysis. Enterovirus infections are suspected to play a role in the development of juvenile-onset diabetes mellitus (sugar diabetes). Newborns infected with an enterovirus may rarely develop severe illness and die from infection. Usually, there are no long-term complications from the mild illnesses or from "aseptic" meningitis. Some patients who have paralysis or encephalitis, however, do not fully recover. Persons who develop heart failure (dilated cardiomyopathy) from myocarditis may require long-term care for their conditions.