Congenital rubella syndrome natural history

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Complications

CRS can result in serious birth defects such as:

• Malformations of the heart (especially patent ductus arteriosus), eyes or brain
• Deafness
• Spleen, liver or bone marrow problems (some of which may disappear shortly after birth)
• Mental retardation
• Small head size (microcephaly)
• Eye defects
• Low birth weight
• Thrombocytopenic purpura
• Hepatomegaly

Prognosis

• The outcome for a child with congenital rubella depends on the severity of problems present.
• Heart defects can often be corrected.
• Damage to the nervous system is permanent.