Cryptosporidiosis laboratory tests
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Laboratory Findings
Image below shows cryptosporidium oocyst in modified acid fast stain.
Stool Test
Diagnosis of cryptosporidiosis is made by examination of stool samples. Because detection of Cryptosporidium can be difficult, patients may be asked to submit several stool samples over several days. Most often, stool specimens are examined microscopically using different techniques (e.g., Acid fast stain|acid-fast staining, direct fluorescent antibody DFA , and/or enzyme immunoassays for detection of Cryptosporidium sp. antigens).
PCR
Molecular methods (e.g., polymerase chain reaction – PCR) are increasingly used in reference diagnostic labs, since they can be used to identify Cryptosporidium spp. at the species level. Tests for Cryptosporidium are not routinely done in most laboratories; therefore, health care providers should specifically request testing for this parasite.