Toxic shock syndrome diagnostic criteria
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]}
Diagnostic Criteria
Diagnosis of TSS and TSLS are strictly based on CDC criteria:
- Body temperature > 38.9 °C (102.02 °F)
- Systolic blood pressure < 90 mmHg
- Diffuse rash, intense etheraderma, blanching ("boiled lobster") with subsequent desquamation, especially of the palms and soles
- Involvement of three or more organ systems:
- GI (vomiting, diarrhea)
- Mucous membrane hyperemia (vaginal, oral, conjunctival)
- Renal failure (serum creatinine > 2x normal)
- Hepatic inflammation (AST, ALT > 2x normal)
- Thrombocytopenia (platelet count < 100,000 / mm³)
- CNS involvement (confusion without any focal neurological findings)